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7.51 Principles of Biochemical Analysis

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Prereq: Permission of instructor
Units: 6-0-6
Lecture: MWF9-10.30 (56-114) Recitation: T2.30,F1 (56-114)

Principles of protein biochemistry, emphasizing structure, equilibrium studies, kinetics, and experimental design. Topics include macromolecular binding and specificity, allosteric systems, mechanisms of inhibition, enzyme principles, single-molecule studies, structure-function relationships, molecular evolution, and library methods. Case studies examine mechanisms of transcription factors, kinases, molecular machines, and other proteins.
L. Case, A. Keating, J. Davis
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