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7.371 Biological and Engineering Principles Underlying Novel Biotherapeutics
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Undergrad (Fall)
Prereq: 7.06
Units: 4-0-8
Credit cannot also be received for 7.37, 10.441, 20.361
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Covers biological and bioengineering principles underlying the development and therapeutic use of recombinant proteins and immune cells. Special attention to monoclonal antibodies and engineered immune system cells as therapeutics; protein- and glyco- engineering to enhance protein function; protein pharmacology and delivery; nucleic acid- based biotherapeutics; generation of functional cells and tissues from embryonic stem cells and iPS cells; and immune cell-cancer cell interactions in cancer immunotherapy.
J. Chen, H. Lodish