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7.371[J] Biological and Engineering Principles Underlying Novel Biotherapeutics

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(Same subject as 20.371[J])
Prereq: 7.06
Units: 4-0-8
Lecture: MW3-5 (Whitehead-7TH)

Covers biological and bioengineering principles underlying the development and therapeutic use of recombinant proteins and immune cells. Special attention to monoclonal antibodies and engineered immune system cells as therapeutics; protein- and glyco- engineering to enhance protein function; protein pharmacology and delivery; nucleic acid- based biotherapeutics; generation of functional cells and tissues from embryonic stem cells and iPS cells; and immune cell-cancer cell interactions in cancer immunotherapy.
J. Chen, H. Lodish
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