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IAP/Spring 2025 Search Results

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20.390[J] Computational Systems Biology: Deep Learning in the Life Sciences
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Not offered academic year 2025-2026Undergrad (Spring)
(Same subject as 6.8711[J])
(Subject meets with 6.8710[J], 20.490, HST.506[J])
Prereq: (6.100B and 7.05) or permission of instructor
Units: 3-0-9
Lecture: TR12.30-2 (10-250)
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Presents innovative approaches to computational problems in the life sciences, focusing on deep learning-based approaches with comparisons to conventional methods. Topics include protein-DNA interaction, chromatin accessibility, regulatory variant interpretation, medical image understanding, medical record understanding, therapeutic design, and experiment design (the choice and interpretation of interventions). Focuses on machine learning model selection, robustness, and interpretation. Teams complete a multidisciplinary final research project using TensorFlow or other framework. Provides a comprehensive introduction to each life sciences problem, but relies upon students understanding probabilistic problem formulations. Students taking graduate version complete additional assignments.
E. Alm, B. Berger
No textbook information available