MIT Subject Listing & Schedule
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20.110[J] Thermodynamics of Biomolecular Systems

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(Same subject as 2.772[J])
Prereq: (Biology (GIR), Calculus II (GIR), Chemistry (GIR), and Physics I (GIR)) or permission of instructor
Units: 5-0-7
Lecture: MWF10 (3-270) Recitation: MW4 (1-242) or TR10 (1-242) or TR11 (1-277) or TR1 (1-277) +final

Equilibrium properties of macroscopic and microscopic systems. Basic thermodynamics: state of a system, state variables. Work, heat, first law of thermodynamics, thermochemistry. Second and third law of thermodynamics: entropy and its statistical basis, Gibbs function. Chemical equilibrium of reactions in gas and solution phase. Macromolecular structure and interactions in solution. Driving forces for molecular self-assembly. Binding cooperativity, solvation, titration of macromolecules.
M. Birnbaum, P. Blainey, S. Manalis
No required or recommended textbooks